As Alzheimer's Drugs Continue to Fail, Researchers Search for Reasons Why Coconut Oil Cures Alzheimer'sA group of New York City’s Mt. Sinai Medical School researchers set out to analyze why and how coconut oil affects Alzheimer’s Disease (AD) patients favorably. They acknowledged some efficacy from coconut oil, and they wanted to know more. Since most drug trials to develop an Alzheimer's drug have failed miserably, the motivation to study coconut oil in order to understand how it positively affects AD was probably motivated by a desire to patent a new drug that could work similar to coconut oil, a natural food that cannot be patented. Their research was based on earlier animal studies of virgin coconut oil’s effect on mouse models of coconut oil as well as other in vitro (lab culture) studies. The researchers also acknowledged the existence of many anecdotal testimonies of AD (Alzheimer’s disease) patients. The Mt. Sinai report was published in the journal Science Direct, Brain Research with the title: Coconut oil decreases expression of amyloid precursor protein (APP) and secretion of amyloid peptides through inhibition of ADP-ribosylation factor 1 (ARF1).