Black cumin seed oil, technically known as Nigella Sativa or N. sativa, has been used for thousands of years for several maladies, disorders, and both infectious and non-infectious diseases, especially throughout ancient Mideast, Egypt, and Greece. Currently, black cumin seeds and oils (from the seeds) are used as traditional medicines in the Mideast as well as parts of Africa and Asia. It's principal and most abundant bioactive phytochemical ingredient is thymoquinone. In addition to the multitude of anecdotal reports demonstrating efficacy and safety, there has been a growing curiosity among modern medical researchers who have been researching black cumin seed oil’s thymoquinone for the past few decades. Two more studies have been added in 2018, both relating to black seed oil's ability to relieve arthritis. One was a review article and the other a human trial study.

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