The Vaccine Science is UnsettledThe foundation of scientific research on human health is the clinical study, and the strength and reliability of conclusions reached is a direct reflection of the study methods used in that research. If the trial design is sound and the research methods followed with integrity, the results will be robust. If not, the results are going to remain open to question and interpretation. One of the most widely repeated phrases bandied about by those who maintain that vaccines very rarely, if ever, cause injury and death is, “the science on vaccines is settled.” Aside from how absurd it is to insist that any science is ever completely settled, such a statement presupposes that vaccine safety and efficacy studies have been rigorous and exhaustive and that their conclusions, therefore, are reliable and authoritative. It would be great if that were the case. Sadly, it is not.